EXTRACTS FROM THE

HOME GUIDE TO MEDICATION

 

Paroxetine

TRADE NAMES:

Aropax, GenRx Paroxetine, Oxetine, Paxtine.

DRUG CLASS:

SSRI antidepressant.

USES:

Treatment and prevention of depression, anxiety, obsessive compulsive disorder, panic attacks, social anxiety disorder, and post-traumatic stress disorder.

DOSAGE:

One to three tablets a day in morning with food.

FORMS:

Tablet of 20mg. (white).

PRECAUTIONS:

Should be used in pregnancy (C) and children with considerable caution. Breast feeding should be ceased if paroxetine prescribed.

Should be used with caution in mania, epilepsy and heart disease.

Should not be stopped suddenly, but dose should be slowly reduced over several days.

Do not take if:-      • taking MAOI antidepressants.

SIDE EFFECTS:

Common: Generally minimal and ease with continued use. Nausea, drowsiness, sweating, tremor, tiredness, dry mouth, sleeplessness, impotence.

Unusual : Headache, fever, poor libido, palpitations, sweating, rash, blurred vision, decreased appetite.

Severe but rare (stop medication, consult doctor): Seizures (fits).

INTERACTIONS:

Other drugs:     • Serious interaction with MAOI.

                    • Anticoagulants (eg. warfarin), thioridazine, phenytoin, tryptophan.

Herbs:            • St.John’s wort, ma huang.

Other substances:     • Use of alcohol with paroxetine is not advised.

PRESCRIPTION:

Yes.

PBS:

Yes.

PERMITTED IN SPORT:

Yes.

OVERDOSE:

Symptoms may include nausea, tremor, dilated pupils, dry mouth and irritability. Death or serious effects have not occurred. Seek medical attention.

OTHER INFORMATION:

One of the antidepressants released in Australia in the 1990s that has dramatically improved the treatment of depression because of its safety and lack of side effects. May take up to two weeks for patient to notice any improvement in symptoms.

    See also Citalopram, Fluoxetine, Fluvoxamine, Sertraline, Venlafaxine

 

 

Pectin

TRADE NAMES:

Bispectin (with kaolin, codeine, aluminium hydroxide, benzoic acid and other ingredients).

Diareze (Tablets - with aluminium hydrochloride, attapulgite; Suspension - with simethicone, attapulgite).

Donnagel (with kaolin, atropine, hyoscine and other ingredients).

Kaomagma with Pectin (with kaolin, aluminium hydroxide, benzoic acid and other ingredients).

Also found in some locally produced preparations.

DRUG CLASS:

Fibre.

USES:

Mild diarrhoea.

DOSAGE:

As required to control diarrhoea.

FORMS:

Tablets, suspension.

PRECAUTIONS:

Safe in pregnancy (A), breast feeding and children over 5 years.

Use with caution in reduced intestinal absorption.

Ensure adequate fluid intake.

SIDE EFFECTS:

Minimal.

INTERACTIONS:

Other drugs:     • May affect absorption of some drugs (eg: digoxin).

PRESCRIPTION:

No.

PBS:

No.

PERMITTED IN SPORT:

Yes.

OVERDOSE:

Not likely to be harmful.

OTHER INFORMATION:

Derived from apple fibre.

    See also Diphenoxylate hydrochloride, Frangula, Kaolin, Ispaghula, Loperamide, Methylcellulose, Psyllium, Sterculia.

 

 

Penicillamine

TRADE NAME:

D-Penamine.

USES:

Severe rheumatoid arthritis, Wilson’s disease, cystinuria, heavy metal poisoning (eg: lead).

DOSAGE:

Rheumatoid disease : One or two tablets, one to three times a day.

Other conditions : Up to 2000mg. a day depending upon severity and response.

FORMS:

Tablets (white) of 125mg. and 250mg.

PRECAUTIONS:

Must not be used in pregnancy (D) unless essential for the life of the mother. Breast feeding should be ceased before use. May be used in children when medically indicated.

Use with caution in liver and kidney disease, brain disorders or feverish.

Avoid surgery if possible.

Regular blood tests essential.

Regular checks of skin, eyes and temperature necessary.

Ensure adequate vitamin B intake.

Patient must be made aware of the adverse effects of this medication before use.

Do not take if:-      • using gold or chloroquine.

SIDE EFFECTS:

Common: Rash, fever, joint pains, enlarged glands, itch.

Unusual : Hair loss, ringing noise in ears, abnormal blood tests, nausea, loss of appetite, vomiting, diarrhoea, blood clots, taste changes.

Severe but rare (stop medication, consult doctor): Significant rash, severe belly pain, yellow skin (jaundice from liver damage), vision disturbances, unusual bleeding or bruising.

INTERACTIONS:

Other drugs:     • Gold, antimalarial drugs (eg. chloroquine), isoniazid, iron supplements.

PRESCRIPTION:

Yes.

PBS:

Yes.

PERMITTED IN SPORT:

Yes.

OVERDOSE:

May cause permanent organ damage. Administer activated charcoal or induce vomiting if medication taken recently. Seek medical attention.

OTHER INFORMATION:

Although it has serious side effects, Penicillamine may give great relief to sufferers of severe rheumatoid arthritis, and may be life saving in heavy metal poisoning. Risks minimal if taken under close supervision of a competent physician.

    See also GOLD

 

PENICILLINS

    Penicillins are the most widely used antibiotics in the world. There are many different types of penicillin now available. They are broad-spectrum antibiotics that kill a wide range of bacteria, and have been used for almost every conceivable type of infection at some time. Unfortunately many bacteria are now becoming resistant to penicillins.

    Allergies to penicillin are not more common than to other drugs, but appear to be so because it is so widely used. Patients who know they have a penicillin allergy should tell their doctors and wear a warning pendant or bracelet. Penicillins may cause a skin rash if given to a patient with glandular fever, and may start a vaginal thrush infection in some women.

    See Amoxycillin, Ampicillin, Benzathine penicillin, Benzyl penicillin, Dicloxacillin, Flucloxacillin, Phenoxymethyl penicillin, Piperacillin, Procaine penicillin, Ticarcillin.